Lynch syndrome: still not a familiar picture
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منابع مشابه
Lynch syndrome: still not a familiar picture
BACKGROUND Germ line mutations in mismatch repair genes underlie Lynch syndrome and predispose carriers for colorectal carcinoma and malignancies in many other organ systems. CASE PRESENTATION A large Lynch syndrome family with 15 affected family members and involvement in 7 organs is reported. It illustrates a lack of awareness and knowledge about this hereditary tumor syndrome among doctors...
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R isk stratification is essential for designing efficacious and cost effective colon cancer screening programmes. One of the most important risk factors for colorectal cancers (CRC) is an inherited predisposition, implicated in 20% of all cases. The spectrum of genetic susceptibility ranges from the low penetrance mutations that modestly increase the colon cancer risk (for example, I 1307K) to ...
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ژورنال
عنوان ژورنال: World Journal of Surgical Oncology
سال: 2008
ISSN: 1477-7819
DOI: 10.1186/1477-7819-6-21